TOMA OS-Seq™ Cancer Assay

Customized to your gene targets

TOMA OS-SeqTM Cancer Assay contain all necessary reagents and step-by-step directions to efficiently prepare sample DNA for sequencing

Laboratories can use TOMA OS-SeqTM Cancer Assay to accurately detect and analyze all alterations in single – and double – stranded DNA from low volume and poor quality tumor tissue

In addition to its standard panel of 131 cancer-associated genes, TOMA’s modular design and chemistry allows us to build custom cancer assays for companies and collaborators who are interested in targeting specific genes.

TOMA ADVANTAGE

OTHER METHODS

Damaged DNA excised to minimize error DNA repair introduces errors and noise
Ultra-efficient adaptor ligation captures single- & double-stranded DNA Whole genome PCR misses all single stranded DNA common to tumor and plasma samples
Capture time reduced to two hours Capture time 1-3 days significant slows turn-around
Single, simple workflow for most sample types Complex, multiple protocols required for different sample types
Detects down to 2% mutant allele frequency (MAF) to identify more actionable changes Misses actionable changes with 5% or higher MAF
Ultra-high sensivity for Copy Number Alterations provides more clinically meaningful results Whole genome PCR distorts original sample ratios, making it difficult to detect Copy Number Alterations

TOMA OS-Seq™ Cancer Assay are for research use only. Not for use in diagnostic procedures.